June 19, 2017

Trust and Credibility in Web-Based Health Information: A Review and Agenda for Future Research

Journal of Medical Internet Research
Original Paper

  • Laura Sbaffi1*, MA, PhD 
  • Jennifer Rowley2*, MSc, PhD 
  • ABSTRACT
    Background: Internet sources are becoming increasingly important in seeking health information, such that they may have a significant effect on health care decisions and outcomes. Hence, given the wide range of different sources of Web-based health information (WHI) from different organizations and individuals, it is important to understand how information seekers evaluate and select the sources that they use, and more specifically, how they assess their credibility and trustworthiness.

    June 14, 2017

    Angioedema suppressed by a combination of anti-histamine and leukotriene modifier

     
    OPEN ACCESS
    Rationale
    Angioedema without co-existent urticaria is due to a limited number of causes, including hereditary and acquired C1 esterase inhibitor deficiency, drug-induced angioedema or idiopathic histaminergic or non-histaminergic angioedema. We describe a cohort of patients with recurrent angioedema whose clinical features and response to medications are distinct from the causes above.

    June 12, 2017

    Computational analysis of multimorbidity between asthma, eczema and rhinitis

    OPEN ACCESS    PEER-REVIEWED
    RESEARCH ARTICLE

    Daniel Aguilar ,Mariona Pinart,Gerard H. Koppelman,Yvan Saeys,Martijn C. Nawijn,Dirkje S. Postma,Mübeccel Akdis,Charles Auffray,Stéphane Ballereau,Marta Benet,Judith García-Aymerich,Juan Ramón González,Stefano Guerra, Josep M. Antó

    Abstract

    Background
    The mechanisms explaining the co-existence of asthma, eczema and rhinitis (allergic multimorbidity) are largely unknown. We investigated the mechanisms underlying multimorbidity between three main allergic diseases at a molecular level by identifying the proteins and cellular processes that are common to them.

    Comparison of the Performance of Skin Prick, ImmunoCAP, and ISAC Tests in the Diagnosis of Patients with Allergy

    Molecules and Cells in Allergy - Original Paper

    Editor's Choice -- Free Access

    Griffiths R.L.M. · El-Shanawany T. · Jolles S.R.A. · Selwood C. · Heaps A.G. · Carne E.M. · Williams P.E. 

    Int Arch Allergy Immunol 2017;172:215-223

    Background: Allergy is diagnosed from typical symptoms, and tests are performed to incriminate the suspected precipitant. Skin prick tests (SPTs) are commonly performed, inexpensive, and give immediate results. Laboratory tests (ImmunoCAP) for serum allergen-specific IgE antibodies are usually performed more selectively.

    June 2, 2017

    Thyroid Autoimmunity: Role of Anti-thyroid Antibodies in Thyroid and Extra-Thyroidal Diseases

    Eleonore Fröhlich1,2 and Richard Wahl1*
    1Internal Medicine (Department of Endocrinology and Diabetology, Angiology, Nephrology and Clinical Chemistry), University of Tuebingen, Tuebingen, Germany 2Center for Medical Research, Medical University Graz, Graz, Austria

    Autoimmune diseases have a high prevalence in the population, and autoimmune thyroid disease (AITD) is one of the most common representatives. Thyroid autoantibodies are not only frequently detected in patients with AITD but also in subjects without manifest thyroid dysfunction. The high prevalence raises questions regarding a potential role in extra-thyroidal diseases. This review summarizes the etiology and mechanism of AITD and addresses prevalence of antibodies against thyroid peroxidase, thyroid-stimulating hormone receptor (TSHR), and anti-thyroglobulin and their action outside the thyroid.

    June 1, 2017

    Quality indicators for the acute and long-term management of anaphylaxis: a systematic review

    Clinical and Translational Allergy
    • Sangeeta DhamiView ORCID ID profile,
    • Aadam Sheikh,
    • Antonella Muraro,
    • Graham Roberts,
    • Susanne Halken,
    • Monserat Fernandez Rivas,
    • Margitta Worm and
    • Aziz SheikhEmail author

    Abstract
    Background
    The quality of acute and long-term anaphylaxis management is variable and this contributes to the poor outcomes experienced by many patients. Clinical practice guidelines have the potential to improve outcomes, but implementing guideline recommendations in routine practice is challenging. Quality indicators have the potential to support guideline implementation efforts.

    May 22, 2017

    Multicentre, non-interventional study to assess the profile of patients with uncontrolled rhinitis prescribed a novel formulation of azelastine hydrochloride and fluticasone propionate in a single spray in routine clinical practice in the UK

    Respiratory medicine
    Research

    Glenis Scadding, David Price, Tariq El-Shanawany, Shahzada Ahmed, Jaydip Ray, Ravishankar Sargur, Nirmal Kumar

    Abstract
    Objective The aims of this study were (1) to characterise the type of patient prescribed MP-AzeFlu (Dymista, a novel formulation of azelastine hydrochloride, fluticasone propionate and excipients in a single spray) in real life in the UK and physicians' reasons for prescribing it and (2) to quantify the personal and societal burden of allergic rhinitis (AR) in the UK prior to MP-AzeFlu prescription.

    May 20, 2017

    IgE-mediated food allergies in children: prevalence, triggers, and management

    REVIEW ARTICLE
    Korean J Pediatr 2017 April;60(4) :99-105.
    Published online 2017 April 15.  
    Sooyoung Lee
    Department of Pediatrics, Ajou University School of Medicine, Suwon, Korea
    Corresponding Author: Sooyoung Lee ,Tel: +82-31-219-5160, Fax: +82-31-219-5169, Email: jsjs87@ajou.ac.kr
    ABSTRACT
    Food allergy (FA) is a serious health problem, and severe FA such as food-induced anaphylaxis can often be life threatening. The incidence of FA has been increasing especially in children. They usually develop early in life and affect up to 10% of children. The 2 most common food allergens worldwide are milk and eggs, while the third one varies depending on the countries: peanuts in the United States and Switzerland, wheat in Germany and Japan, tree nuts in Spain, sesame in Israel, and walnuts in Korea.

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