October 21, 2017

Non-allergic rhinitis: Position paper of the European Academy of Allergy and Clinical Immunology

Volume 72, Issue 11November 2017 Pages 1657–1665

POSITION PAPER

P. W. Hellings, L. Klimek, C. Cingi, I. Agache, C. Akdis, C. Bachert, J. Bousquet, P. Demoly, P. Gevaert, V. Hox, C. Hupin, L. Kalogjera, F. Manole, R. Mösges, J. Mullol, N. B. Muluk, A. Muraro, N. Papadopoulos, R. Pawankar, C. Rondon, M. Rundenko, S. F. Seys, E. Toskala, L. Van Gerven, L. Zhang, N. Zhang, W. J. Fokkens

Abstract

This EAACI position paper aims at providing a state-of-the-art overview on nonallergic rhinitis (NAR). A significant number of patients suffering from persistent rhinitis are defined as nonallergic noninfectious rhinitis (NANIR) patients, often denominated in short as having NAR. NAR is defined as a symptomatic inflammation of the nasal mucosa with the presence of a minimum of two nasal symptoms such as nasal obstruction, rhinorrhea, sneezing, and/or itchy nose, without clinical evidence of endonasal infection and without systemic signs of sensitization to inhalant allergens.

Methotrexate Versus Cyclosporine in Adults with Moderate-to-Severe Atopic Dermatitis: A Phase III Randomized Noninferiority Trial

Catherine Goujon, MD

Correspondence information about the author MD Catherine Goujon

Email the author MD Catherine Goujon

Manuelle Viguier, MD, PhD

Delphine Staumont-Sallé, MD, PhD

Claire Bernier, MD

Gérard Guillet, MD, PhD

Morad Lahfa, MD

Marie-Christine Ferrier Le Bouedec, MD

Frédéric Cambazard, MD, PhD

David Bottigioli, BA

Sophie Grande, MD

Karima Dahel, MD

Frédéric Bérard, MD, PhD

Muriel Rabilloud, MD, PhD

Catherine Mercier, PhD

Jean-François Nicolas, MD, PhD

DOI: http://dx.doi.org/10.1016/j.jaip.2017.07.007

Article Info

Chronic Spontaneous Urticaria: Pathogenesis and Treatment Considerations

Allergy Asthma Immunol Res. 2017 Nov;9(6):477-482. https://doi.org/10.4168/aair.2017.9.6.477

Allen P. Kaplan
Department of Medicine, Division of Pulmonary and Critical Care Medicine, Allergy and Clinical Immunology, Medical University of South Carolina, Charleston, SC, USA.
Correspondence to: Allen P. Kaplan, MD, Department of Medicine, Division of Pulmonary and Critical Care Medicine, Allergy and Clinical Immunology, Medical University of South Carolina, Charleston, 171 Ashley Avenue, Charleston, SC 29425, USA. Tel: +1-843-729-0264; Fax: +1-843-722-1253; Email: kaplana@musc.edu
Go to: Abstract
The treatment of chronic spontaneous urticaria begins with antihistamines; however, the dose required typically exceeds that recommended for allergic rhinitis. Second-generation, relatively non-sedating H₁-receptor blockers are typically employed up to 4 times a day.

Open Access
Creative Commons

ORIGINAL ARTICLE

Authors

DOI: 10.1111/all.13213 View/save citation
Abstract

Background

Allergy immunotherapy (AIT) is the only treatment for allergic rhinitis (AR) and/or allergic asthma (AA) with long-term efficacy. However, there are few real-life data on the progression of AR and/or AA in patients receiving AIT.

Price, Alexandra MS*; Ramachandran, Sarika MD†; Smith, Gideon P. MD, PhD‡; Stevenson, Mary L. MD†; Pomeranz, Miriam K. MD†; Cohen, David E. MD, MPH†

Dermatitis: March/April 2015 - Volume 26 - Issue 2 - p 78–88

doi: 10.1097/DER.0000000000000087

Reviews

Oral allergy syndrome (OAS) or pollen-food allergy syndrome (PFS) is a hypersensitivity reaction to plant-based foods, manifesting most commonly with pruritus of the lips, tongue, and mouth. Unlike simple food allergy, OAS requires prior sensitization to a cross-reacting inhalant allergen rather than direct sensitization to a specific food protein. In this review, we summarize the clinical features and pathophysiology of OAS and provide an overview of known pollen-food associations.

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September 28, 2017

Molecular aspects of allergens in atopic dermatitis

Curr Opin Allergy Clin Immunol. 2017 August; 17(4): 269–277.

Published online 2017 July 28. doi: 10.1097/ACI.0000000000000378

PMCID: PMC5540349

Raffaela Campana,^a Sheron Dzoro,^a Irene Mittermann,^a Elena Fedenko,^b Olga Elisyutina,^b Musa Khaitov,^b Alexander Karaulov,^c and Rudolf Valenta^a

Author information ► Copyright and License information ►

Abstract

Purpose of review

Molecular allergology uses pure, mainly recombinant and structurally defined allergen molecules and allergen-derived epitopes to study mechanisms of IgE-associated allergy, to diagnose, and even predict the development of allergic manifestations and to treat and prevent IgE-associated allergies.